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The Mystery Behind the Runner’s High: Beyond Endorphins

by Benjamin FitzwaterJanuary 16, 2025January 24, 2025

Study: Runner's High Has This in Common With Orgasms and Weed - Men's Journal

The sensation of boundless energy and joy many feel post-exercise, often dubbed the “runner’s high,” has long been attributed to endorphins. However, recent insights suggest another molecule might be the key player in this feel-good phenomenon.

Ever felt an unstoppable urge to continue running even after miles under your belt? That’s the runner’s high for you. It’s a state of profound relaxation and happiness, momentarily easing the discomfort from prolonged physical activity. Yet, this fleeting bliss isn’t a universal experience for all exercisers.

This discussion delves into the essence of a runner’s high, exploring its origins and why achieving this state might be more challenging than anticipated.

Understanding the Runner’s High

A runner’s high is an ephemeral state of euphoria following intense or prolonged physical activity. This state is often accompanied by reduced anxiety and diminished perception of pain. However, attaining a runner’s high is not a given for every runner or exerciser, partly because “euphoria” is subjective and challenging to quantify. Additionally, reaching the required intensity or duration of exercise for a runner’s high may not be feasible for everyone.

The Body and Brain’s Reaction to Running

While running offers numerous benefits beyond cardiovascular health, the “runner’s high” has been traditionally linked to the release of endorphins, the body’s “feel-good” chemicals. These neurochemicals produce happiness and pleasure and act as natural analgesics during physical exertion.

However, recent studies suggest that endorphins, due to their large molecular size preventing them from crossing the blood-brain barrier, might not be directly responsible for the runner’s high. The spotlight has now shifted to endocannabinoids, smaller molecules capable of influencing the brain’s receptors, mirroring the effect of THC found in cannabis.

Reassessing Endorphins and Endocannabinoids

The endocannabinoid system, affected by exercise-induced endocannabinoids like anandamide, may play a crucial role in the runner’s high, offering euphoria and relaxation.

Despite the promising link between endocannabinoids and the runner’s high, the current understanding largely stems from animal studies, with human research still evolving.

The Wide Array of Running Benefits

Although not everyone will experience a runner’s high, running consistently offers myriad benefits, from reducing anxiety and depression to improving memory, flexibility, and overall immune response.

In Essence

The runner’s high, an elusive state of bliss post-exercise, may owe its effects to endocannabinoids rather than endorphins. While the precise triggers and accessibility of a runner’s high remain under investigation, the array of physical and mental benefits from regular exercise underscores the value of staying active, with or without the euphoria.

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